Perspectives of Cosmesis following Breast Conservation for Multifocal and Multicentric Breast Cancers

Perspectives of Cosmesis following Breast Conservation for Multifocal and Multicentric Breast Cancers

Background. Contemporary data suggest that breast conservation treatment (BCT) for multifocal and multicentric breast cancer (MFMCBC) may be appropriate with noninferior local control rates. However, there is a paucity of data to evaluate patient's satisfaction with cosmetic outcomes after BCT for MFMCBC. This study was performed to bridge this information gap. Methods. All patients treated at ...

Oncoplastic Surgery of Multicentric (Multifocal) Breast Cancer

The breast-conserving treatment, in essence, implies not only providing breast-conserving surgery (BCS), but also adjuvant radiation therapy, that significantly reduces the risk of disease loco-regional and distant recurrence and is considered as an integral part of breast cancer conservative treatment [1,2]. Traditionally, appearance of more than one malignant tumor, in one or several breast q...

Comparison of the histopathology and prognosis of bilateral versus unilateral multifocal multicentric breast cancers

BACKGROUND Multiple breast cancers may present with different clinical and biological characteristics. The data indicate that multifocal (MF), multicentric (MC), and bilateral synchronous (BS) breast cancers (BC) are more aggressive and have an equivalent or moderately poorer survival rate compared with unilateral cases. However, a comparison of these multiple breast cancers has not been covere...

Multifocal, multicentric, and contralateral breast cancers: MR imaging in preoperative assessment of local extent disease

Tumor size and survival in multicentric and multifocal breast cancer.

PURPOSE Current AJCC/UICC staging of early breast cancer defines tumor stage using the largest focus, adding the suffix "(m)" to indicate multiplicity. This method may underestimate the total tumor burden in multifocal and multicentric breast cancer (MMBC). This study examines other measures of tumor size in MMBC to determine which provides the best fit in a multivariate model for survival outc...